711 HPW - Institutional Review Board

The mission of the Air Force Research Laboratory's Institutional Review Board (IRB) is to facilitate excellence in human-performance and technological research that advances warfighting capabilities in air, space, and cyberspace by efficiently processing and professionally evaluating proposals for scientific validity and uncompromising protection of the rights and welfare of volunteer subjects.

Investigators should visit the Information Center Page (CAC required) to download submission templates and review processes for submission of protocols. They should also review applicable Regulations, including the most recent versions of AFI 40-102 Protection of Human Subjects and Adherence to Ethical Standards in Air Force Supported Research and AFRLI 40-102 Protection of Human Subjects in Research, both of which were substantially rewritten in the latter half of 2014.

All primary investigators, associate investigators, and other key personnel engaged in AFRL-supported human-subject research must have completed the AFRL-designated  annual required training found on ADLS (for Government Civilians and Military Personnel) and every three years complete the modules hosted by the Collaborative Institutional Training Initiative (CITI).


711 HPW/IR
2245 Monahan Way, Bldg 29, Rm 201
Wright-Patterson AFB, OH 45433

Intramural submissions: AFRL.IR.PROTOCOLMANAGEMENT@us.af.mil
Extramural submissions: AFRL.IR.HRPO@us.af.mil


1. INSTRUCTIONS – Extramural Submission Instructions
2. CHECKLIST – Extramural Initial Submission Checklist
3. INFO SHEET – DoD Supported Human Subjects Research


10 USC 980 Limitations On Use Of Humans as Experimental Subjects
21 CFR 50 Protection of Human Subjects
21 CFR 56 Protection of Human Subjects
32 CFR 219 Protection of Human Subjects
AFI 40-402 Protection of Human Subjects in Biomedical and Behavioral Research
AFRLI 40-402 Using Human Subjects in Research
DoD 5400.11-R Department of Defense Privacy Program 
DoD 6025.18-R DoD Health Information Privacy Regulation
DoD Directive 3216.02 Protection of Human Subjects and Adherence to Ethical Standards in DoD Supported Research